How long after starting stimulation will egg collection be?
Ovulation induction may last approximately for 12 days.
What about the monitoring during stimulation phase of treatment?
Monitoring normally takes place during the stimulation phase of the treatment (e.g. Blood tests for oestrogen, progesterone and ultrasound scans). Follicle measurements and hormone levels in the blood will indicate the time for oocyte aspiration.
How many eggs will you be expecting at egg collection?
10-12 eggs are expected to retrieve.
Will I have a general anesthetic or sedation during the procedure?
You will have sedation during oocyte pick-up and not feel any pain.
Is there anything we can do to improve the quality of the eggs or the sperm?
At this moment you cannot do anything to increase the quality of egg and sperm. Stop smoking if you do.
How many days after egg collection will be embryo transfer (on average)?
Embryo transfer is done 2,3 or 5 days after egg collection.
What is blastocyst transfer?
Embryos become blastocsyt if they are kept out of the body for 5 days. Blastocyst transfer is performed in our center in cases that have more than 10 eggs.
How do you grade the embryos?
Embryo grading is performed according to number and the appearance of the cells (blastomers).
Under what conditions would you freeze any 'spare' embryos?
If spare embryos are good in shape and minister of blastomers is appropriate it means that they are worth to freeze.
Will I be receiving any additional treatment during this cycle of ICSI?
We generally recommend aspirin and corticosteroids after embryo transfer.
What are the risks that we need to be aware of? What is ovarian hyperstimulation?
Every patient responds on the ovarian stimulation differently. Approximately 15% of the cases may be cancelled due to poor ovarian response or ovarian hyper stimulation. Sometimes ovaries respond to ovulation induction agents more than expected and get severely enlarged. Fluid may accumulate in the abdomen and disturb woman. This is so called ovarian hyperstimulation. These problems resolve in 2 weeks. However, 1% of hyperstimulated women may need to be hospitalized to follow breathing and urine output.
Another main reason for canceling treatment is the non-presence of sperm in the azospermic patient after the testicular biopsy procedure (TESE).
What is the success rate of the treatment?
The success rate of in vitro fertilization and microinjection is obtained by dividing the number of couples who have children with these methods by the number of couples who begin the treatment process. The global success rate of such procedures is approximately 35%. This percentage reflects the average of every age group. However, if patients are divided into groups by age, success rate becomes 60-70% for young women between 20-30 years of age, declines to 50% after age of 35 and finally drops to 25% after age of 40.
The most important cause of this decline is the advanced age and bad quality eggs obtained in these women. In general, 30 of every 100 couples who begin treatment end up with a child. However, it would be misleading for every patient to use this percentage when evaluating their own condition because the causes of infertility, source of sperm, the number of previous attempt or pregnancy also affect pregnancy rate.